Narcolepsy: Understanding the sleep-wake cycle

Lack of sleep is a common complaint but for many, falling asleep involuntarily during the day,  AKA narcolepsy, poses a very real and dangerous problem.
A new study from the Montreal Neurological Institute (MNI) at McGill University demonstrates interestingly, that sleep-wake states are regulated by two different types of nerve cells (neurons), melanin-concentrating hormone (MCH) neurons [...]

Cephalons Provigil may be addictive

Provigil, a narcolepsy drug increasingly used by healthy people to boost brain performance, may be addictive in vulnerable people and should be monitored, U.S. drug abuse experts said on Tuesday.
A pilot study on 10 healthy men found that at normal doses, the Cephalon Inc (CEPH.O) drug known generically as modafinil increases levels of the reward [...]

Management of Excessive Daytime Sleepiness Reviewed

Practice recommendations to diagnose and treat excessive daytime sleepiness in the family practice setting are reviewed in an article published in the March 1 issue of American Family Physician.
“About 20 percent of adults in the United States report a level of daytime sleepiness sufficient to interfere with daily activities, and excessive daytime sleepiness is the [...]

Off-label Provigil might be addictive

Remember all those scientists who admitted to Nature that they sometimes used Provigil–Cephalon’s stay-awake drug for folks with sleep apnea/narcolepsy/shift work syndrome–to make them more productive?
Well, they might want to turn their more-productive brains toward analyzing the potential risks.
A new study shows that Provigil isn’t the benign little puppy it seemed to be.
Word was, Provigil [...]